ChromoZinc - The key to complete diabetic management
Reliance Formulation (Pvt.) Ltd. provides the doctor with a powerful armamentarium to fight and keep in control blood sugar. ChromoZinc is not a substitute to a doctor’s prescription in sugar control. ChromoZinc is the key to complete a doctor’s prescription in the management of diabetes.
ChromoZinc contains:
Chromium picolinate: 500 mcg
Zinc sulphate monohydrate: 27.5 mg
Methylcobalamin: 750 mcg
Alpha-lipoic acid: 100 mg,
Vitamin B6: 3 mg
Folic acid: 1mg
Chromium
A highly refined diet that contains too few micronutrients has been recognized as the dominant factor in the rising incidence of diabetes and other insulin related conditions. Among the missing micronutrients, chromium has the greatest impact on insulin response. Until recently, few physicians recognized the importance of supplementing chromium in the management of diabetes. However, research has revealed that chromium plays an important role` in amplifying insulin response in diabetics.
Chromium is now proven to be the key to complete the diabetes management. We all know that insulin is a hormone whose primary role is to regulate the body's response to carbohydrates, proteins and fats.
Insulin is produced in the pancreas. Following a meal the pancreas releases insulin into the bloodstream, as glucose, or blood sugar, levels from the digested meal begin to rise; Glucose is the primary fuel for energy production within all body tissues including the brain. But it can't get into cells without the help of insulin. The more the sugar that enters the blood, the more the insulin is required to transport it into cells. Eating refined carbohydrates and sugary foods quickly raises glucose levels making these foods particularly troublesome for anyone with a blood sugar imbalance such as diabetes.
While glucose transport is the primary role of insulin, chromium's main function is increasing insulin's efficiency in regulating blood sugar levels. But this hormone produces much more complex and far-reaching effects. These include the transport of amino acids and electrolytes into cells, several enzymatic activities and cellular growth. Numerous studies show that chromium alters lipoprotein abnormalities (unhealthy LDL and HDL levels) that are believed to increase the risk of cardiovascular disease. Chromium supplementation also appears useful in treating obesity in other research, increasing lean muscle mass and improving athletic performance.
Symptoms of chromium deficiency;
Ø Fasting hyperglycemia (too much of fasting blood sugar)
Ø Hypoglycemia (to little of blood sugar)
Ø Elevated percentage of fat in the body
Ø Peripheral neuropathy
Ø Fatigue
Ø Anxiety
A minimum of 200 mcg of chromium daily is needed for at least three months to have a noticeable effect on insulin response. Anyone with diabetes who uses insulin should consult with a healthcare provider about chromium supplements, since the insulin dosage may have to be adjusted. If required up to 500 mcg can be administered.
What is chromium picolinate?
This popular nutritional supplement is a combination of the element chromium and picolinic acid. Chromium is a naturally occurring mineral, trace amounts of which are found in everyday foods like meat, poultry, fish, and whole-grain breads. When foods are processed, they are stripped of natural chromium, making our diets generally very low in chromium; studies estimate an average daily chromium consumption of 33 mcg in an average non-vegetarian diet.
In 1968, it was demonstrated that when subjects do not receive adequate levels of chromium, insulin is not optimally effective, and damage to insulin-dependent systems can occur (Schroeder, 1968). This led the FDA to recommend a daily chromium intake of approximately 130 mcg (100 mcg chromium picolinate is equivalent to 23mcg elemental chromium), as infinitesimal amounts of chromium are needed to aid the transport of blood glucose across cell membranes
Zinc sulphate monohydrate
Diabetics should probably take zinc supplements! Zinc plays a key role in the regulation of insulin production by pancreatic tissues and glucose utilization by muscles and fat cells.
The abilities to synthesize and secrete insulin and use glucose are impaired in the zinc deficient state. Intestinal zinc absorption rates and plasma zinc levels in diabetic patients are reduced. Zinc is involved in the regulation of insulin receptor-initiated signal transduction mechanisms and insulin receptor synthesis.
Scientists at Notre Dame* and at the University of Illinois have discovered that zinc has an insulin-like effect on the manifestation of diabetes.
Insulin, they note, promotes the transport of glucose and amino acids (proteins) and decreases the breakdown of muscles while healthfully enhancing their buildup.“.... failure to enhance glucose transport, " they say, "into insulin-sensitive cells is a hallmark of diabetes [emphasis added.] They have found that zinc enhances this glucose movement.
Zinc Sulphate 200mg (45mg elemental Zinc) - Zinc is alos documented to be an essential element for normal growth and good vision.
Methylcobalamin
Methylcobalamin is a type of Vitamin B12. Vitamin B12 comes in several kinds including hydroxy-, cyano-, and adenosyl-, but only the methyl form is used in the central nervous system.
Deficiency states are fairly common and vitamin B12 deficiency mimics many other disease states of a neurological or psychological kind, and it causes anemia. Cyanocobalamin (the kind in vitamin supplements) is converted by the liver into methylcobalamin but not in therapeutically significant amounts. Vitamin B12 deficiency is caused by a wide range of factors including low gastric acidity (common in older people,) use of acid blockers such as PPI’s or H2A’s or excessive laxative use, lack of intrinsic factor, poor absorption from the intestines, lack of Calcium, heavy metal toxicity, or excessive Vitamin B12 degradation.
Methylcobalamin donates methyl groups to the myelin sheath that insulates nerve fibers and regenerates damaged neurons. In a B12 deficiency, toxic fatty acids destroy the myelin sheath but high enough doses of B12 can repair it.
Methylcobalamin supplements increase alertness and body temperature. Methylcobalamin may slightly help those with diabetic neuropathy. Methylcobalamin has been found to be helpful in Bell's palsy. Methylcobalamin taken orally is effective in the treatment of pernicious anemia, says a Japanese study. Methylcobalamin may inhibit the ototoxic (hearing damage) side effects of the antibiotic Gentamycin.
Despite intensive searches for therapeutic agents, few substances have been convincingly shown to enhance nerve regeneration in patients with peripheral neuropathies. Recent biochemical evidence suggests that an ultra-high dose of methylcobalamin (methyl-B12) may up-regulate gene transcription and thereby protein synthesis.
Alpha-Lipoic Acid
It is also a potent biological antioxidant. Alpha-lipoic acid was once thought to be a vitamin for animals and humans. It is made endogenously in humans - the details of its synthesis are still not fully understood. There are, however, certain situations, for example, diabetic polyneuropathy, where alpha-lipoic acid might have conditional essentiality.
Recent research indicates that the antioxidant roles of alpha-lipoic acid may confer several health benefits. Alpha-lipoic acid is found widely in plant and animal sources.
Alpha-lipoic acid is approved in Germany as a drug for the treatment of polyneuropathies, such as diabetic and alcoholic polyneuropathies, and liver disease.
Actions And Pharmacology
Mechanism Of Action
Alpha-lipoic acid and its reduced metabolite, dihydrolipoic acid (DHLA), form a redox couple and may scavenge a wide range of reactive oxygen species. Both alpha-lipoic acid and DHLA can scavenge hydroxyl radicals, the nitric oxide radical, peroxynitrite, hydrogen peroxide and hypochlorite. Alpha-lipoic acid, but not DHLA, may scavenge singlet oxygen, and DHLA, but not alpha-lipoic acid, may scavenge superoxide and peroxyl reactive oxygen species.
Further, alpha-lipoic acid and its redox couple DHLA have been found to have antioxidant activity in aqueous, as well as in lipophilic regions, and in extracellular and intracellular environments. Finally, with regard to alpha-lipoic acid's antioxidant activity, alpha-lipoic acid appears to participate in the recycling of other important biologic antioxidants, such as vitamins E and C, ubiquinone and glutathione.
Exogenous alpha-lipoic acid has been shown to increase ATP production and aortic blood flow during reoxygenation after hypoxia in a working heart model.
Pharmacokinetics
Alpha-lipoic acid is absorbed from the small intestine and distributed to the liver via the portal circulation and to various tissues in the body via the systemic circulation.
Indications and Usage
Research Summary on Alpha Lipoic acid
Supplemental alpha-lipoic acid may lower blood glucose levels. Those with diabetes on antidiabetic medication should have their blood glucose monitored and antidiabetic drug dose appropriately adjusted, if necessary, to avoid possible hypoglycemia.
In some experiments, alpha lipoic acid, administered for up to three months, significantly reversed the increase in nerve vascular resistance. Nerve conduction velocity was entirely restored in some nerve groups after three months of treatment.
In a larger, multi-center, double blind, randomized, placebo-controlled study of 328 patients with type 2 diabetes, significant improvements were recorded in several clinical measures of diabetic polyneuropathy, including pain, numbness, paresthesia and burning sensations. These results were evident after three weeks of intravenous lipoic acid given five times weekly in doses of 600 and 1200 milligrams.
There is evidence, too, that lipoic acid may help prevent or slow the development of the atherosclerosis for which diabetics are at higher risk. It may do this, in part, through a gene-regulatory mechanism that helps prevent endothelial cell activity that has been implicated in the progression of atherosclerosis.
With respect to atherosclerosis, in general, lipoic acid's antioxidant and metabolic effects appear to offer some protection, as demonstrated in various animal models. Recently, researchers demonstrated, in a 16-week randomized trial, that lipoic acid, in oral doses of 600 milligrams daily for eight weeks, significantly inhibits the oxidation of LDL-cholesterol in healthy human subjects. The supplements also significantly reduced levels of F-2 isoprostanes, markers of oxidative stress. In this study, lipoic acid proved to be superior to vitamin E in decreasing levels of plasma protein carbonyls. Protein oxidation and LDL-cholesterol oxidation are implicated in heart disease.
Claims that alpha lipoic acid slows aging of the brain and is an anti-aging substance generally seem to be related to its potent antioxidant properties. Direct proof of anti-aging is lacking, but there is some animal work suggestive of some possible anti-aging effects.
Because of lack of long-term safety data, alpha-lipoic acid should be avoided by pregnant women and nursing mothers.
Those with diabetes and problems with glucose intolerance are cautioned that supplemental alpha-lipoic acid may lower blood glucose levels. Blood glucose should be monitored and antidiabetic drug dose adjusted, if necessary, to avoide possible hypoglycemia.
Adverse Reactions
To date, alpha-lipoic acid in doses up to 600 milligrams daily has been well tolerated.
Interactions
Supplemental alpha-lipoic acid may lower blood glucose levels. Those with diabetes on antidiabetic medication should have their blood glucose monitored and antidiabetic drug dose appropriately adjusted, if necessary, to avoid possible hypoglycemia.
Alpha-lipoic acid is available as a racemic mixture of D- and L- entantiomers. Some studies showing significant antioxidant effects have used doses of the racemic mixture of 600 milligrams daily.
Vitamin B6 (Pyridoxine)
Vitamin B6, also called pyridoxine, is one of eight water-soluble B vitamins. The B vitamins help the body to convert carbohydrates into glucose (sugar), which is "burned" to produce energy. These vitamins, often referred to as the B complex, are also essential in the metabolism of fats and protein. B complex vitamins also play an important role in maintaining muscle tone in the gastrointestinal tract and promoting the health of the nervous system, skin, hair, eyes, mouth, and liver
Uses
Heart Disease
Low dietary intake of vitamin B6 is associated with higher risk of having heart disease. This may be related to the fact that vitamin B6, together with vitamin B9 (folic acid) and vitamin B12, help to keep homocysteine levels under control. Homocysteine is an amino acid. Elevated levels of this amino acid are associated with increased risk of heart disease and increased risk of stroke. Preliminary evidence suggests that vitamin B6 may help control blood sugar in people with diabetes. In a study of people with diabetes, those who received pyridoxine alpha-ketoglutarate (a form of vitamin B6) for one month experienced significant reductions in fasting blood sugar levels compared to those who did not receive the supplement. More research in this area is needed before conclusions can be drawn about the relationship between vitamin B6 and diabetes.
Folic acid:
Folic acid deficiency is widespread and is associated with an increased risk for heart disease, cancer, depression and many other disorders. There is no question that folic acid is extremely important to health and well-being. Not only is it important for heart health, mental health and women's health, but also it is now also clear that it affects many other facets of health and disease. Researchers at the Cleveland Clinic Foundation have found that patients with end- stage renal disease have extremely high homocysteine levels and can be protected from cardiovascular events by supplementing with folic acid, vitamins B6 and B12. Diabetes patients tend to have high homocysteine levels and folate is especially important for them. Recent research has also shown that low folate levels (high homocysteine levels) are implicated in age-related hearing loss, psoriasis, and restless leg syndrome.
It is indeed astounding that one single vitamin, folic acid, can have such a profound effect on our health and yet perhaps it is not so surprising when one considers its vital role in DNA synthesis and homocysteine metabolism.
ChromoZinc, therefore, is the indispensable addition in a doctor’s armamentarium while managing diabetes mellitus and diabetic neuropathy.
ChromoZinc contains:
Chromium picolinate: 500 mcg
Zinc sulphate monohydrate: 27.5 mg
Methylcobalamin: 750 mcg
Alpha-lipoic acid: 100 mg,
Vitamin B6: 3 mg
Folic acid: 1mg
Chromium
A highly refined diet that contains too few micronutrients has been recognized as the dominant factor in the rising incidence of diabetes and other insulin related conditions. Among the missing micronutrients, chromium has the greatest impact on insulin response. Until recently, few physicians recognized the importance of supplementing chromium in the management of diabetes. However, research has revealed that chromium plays an important role` in amplifying insulin response in diabetics.
Chromium is now proven to be the key to complete the diabetes management. We all know that insulin is a hormone whose primary role is to regulate the body's response to carbohydrates, proteins and fats.
Insulin is produced in the pancreas. Following a meal the pancreas releases insulin into the bloodstream, as glucose, or blood sugar, levels from the digested meal begin to rise; Glucose is the primary fuel for energy production within all body tissues including the brain. But it can't get into cells without the help of insulin. The more the sugar that enters the blood, the more the insulin is required to transport it into cells. Eating refined carbohydrates and sugary foods quickly raises glucose levels making these foods particularly troublesome for anyone with a blood sugar imbalance such as diabetes.
While glucose transport is the primary role of insulin, chromium's main function is increasing insulin's efficiency in regulating blood sugar levels. But this hormone produces much more complex and far-reaching effects. These include the transport of amino acids and electrolytes into cells, several enzymatic activities and cellular growth. Numerous studies show that chromium alters lipoprotein abnormalities (unhealthy LDL and HDL levels) that are believed to increase the risk of cardiovascular disease. Chromium supplementation also appears useful in treating obesity in other research, increasing lean muscle mass and improving athletic performance.
Symptoms of chromium deficiency;
Ø Fasting hyperglycemia (too much of fasting blood sugar)
Ø Hypoglycemia (to little of blood sugar)
Ø Elevated percentage of fat in the body
Ø Peripheral neuropathy
Ø Fatigue
Ø Anxiety
A minimum of 200 mcg of chromium daily is needed for at least three months to have a noticeable effect on insulin response. Anyone with diabetes who uses insulin should consult with a healthcare provider about chromium supplements, since the insulin dosage may have to be adjusted. If required up to 500 mcg can be administered.
What is chromium picolinate?
This popular nutritional supplement is a combination of the element chromium and picolinic acid. Chromium is a naturally occurring mineral, trace amounts of which are found in everyday foods like meat, poultry, fish, and whole-grain breads. When foods are processed, they are stripped of natural chromium, making our diets generally very low in chromium; studies estimate an average daily chromium consumption of 33 mcg in an average non-vegetarian diet.
In 1968, it was demonstrated that when subjects do not receive adequate levels of chromium, insulin is not optimally effective, and damage to insulin-dependent systems can occur (Schroeder, 1968). This led the FDA to recommend a daily chromium intake of approximately 130 mcg (100 mcg chromium picolinate is equivalent to 23mcg elemental chromium), as infinitesimal amounts of chromium are needed to aid the transport of blood glucose across cell membranes
Zinc sulphate monohydrate
Diabetics should probably take zinc supplements! Zinc plays a key role in the regulation of insulin production by pancreatic tissues and glucose utilization by muscles and fat cells.
The abilities to synthesize and secrete insulin and use glucose are impaired in the zinc deficient state. Intestinal zinc absorption rates and plasma zinc levels in diabetic patients are reduced. Zinc is involved in the regulation of insulin receptor-initiated signal transduction mechanisms and insulin receptor synthesis.
Scientists at Notre Dame* and at the University of Illinois have discovered that zinc has an insulin-like effect on the manifestation of diabetes.
Insulin, they note, promotes the transport of glucose and amino acids (proteins) and decreases the breakdown of muscles while healthfully enhancing their buildup.“.... failure to enhance glucose transport, " they say, "into insulin-sensitive cells is a hallmark of diabetes [emphasis added.] They have found that zinc enhances this glucose movement.
Zinc Sulphate 200mg (45mg elemental Zinc) - Zinc is alos documented to be an essential element for normal growth and good vision.
Methylcobalamin
Methylcobalamin is a type of Vitamin B12. Vitamin B12 comes in several kinds including hydroxy-, cyano-, and adenosyl-, but only the methyl form is used in the central nervous system.
Deficiency states are fairly common and vitamin B12 deficiency mimics many other disease states of a neurological or psychological kind, and it causes anemia. Cyanocobalamin (the kind in vitamin supplements) is converted by the liver into methylcobalamin but not in therapeutically significant amounts. Vitamin B12 deficiency is caused by a wide range of factors including low gastric acidity (common in older people,) use of acid blockers such as PPI’s or H2A’s or excessive laxative use, lack of intrinsic factor, poor absorption from the intestines, lack of Calcium, heavy metal toxicity, or excessive Vitamin B12 degradation.
Methylcobalamin donates methyl groups to the myelin sheath that insulates nerve fibers and regenerates damaged neurons. In a B12 deficiency, toxic fatty acids destroy the myelin sheath but high enough doses of B12 can repair it.
Methylcobalamin supplements increase alertness and body temperature. Methylcobalamin may slightly help those with diabetic neuropathy. Methylcobalamin has been found to be helpful in Bell's palsy. Methylcobalamin taken orally is effective in the treatment of pernicious anemia, says a Japanese study. Methylcobalamin may inhibit the ototoxic (hearing damage) side effects of the antibiotic Gentamycin.
Despite intensive searches for therapeutic agents, few substances have been convincingly shown to enhance nerve regeneration in patients with peripheral neuropathies. Recent biochemical evidence suggests that an ultra-high dose of methylcobalamin (methyl-B12) may up-regulate gene transcription and thereby protein synthesis.
Alpha-Lipoic Acid
Alpha-lipoic acid, also known as thioctic acid, is a disulfide compound that is a cofactor in vital energy-producing reactions in the body.
It is also a potent biological antioxidant. Alpha-lipoic acid was once thought to be a vitamin for animals and humans. It is made endogenously in humans - the details of its synthesis are still not fully understood. There are, however, certain situations, for example, diabetic polyneuropathy, where alpha-lipoic acid might have conditional essentiality.
Recent research indicates that the antioxidant roles of alpha-lipoic acid may confer several health benefits. Alpha-lipoic acid is found widely in plant and animal sources.
Alpha-lipoic acid is approved in Germany as a drug for the treatment of polyneuropathies, such as diabetic and alcoholic polyneuropathies, and liver disease.
Actions And Pharmacology
Alpha-lipoic acid has biological antioxidant activity, antioxidant recycling activity and activity in enhancing biological energy production.
Mechanism Of Action
Alpha-lipoic acid and its reduced metabolite, dihydrolipoic acid (DHLA), form a redox couple and may scavenge a wide range of reactive oxygen species. Both alpha-lipoic acid and DHLA can scavenge hydroxyl radicals, the nitric oxide radical, peroxynitrite, hydrogen peroxide and hypochlorite. Alpha-lipoic acid, but not DHLA, may scavenge singlet oxygen, and DHLA, but not alpha-lipoic acid, may scavenge superoxide and peroxyl reactive oxygen species.
Further, alpha-lipoic acid and its redox couple DHLA have been found to have antioxidant activity in aqueous, as well as in lipophilic regions, and in extracellular and intracellular environments. Finally, with regard to alpha-lipoic acid's antioxidant activity, alpha-lipoic acid appears to participate in the recycling of other important biologic antioxidants, such as vitamins E and C, ubiquinone and glutathione.
Exogenous alpha-lipoic acid has been shown to increase ATP production and aortic blood flow during reoxygenation after hypoxia in a working heart model.
Pharmacokinetics
Alpha-lipoic acid is absorbed from the small intestine and distributed to the liver via the portal circulation and to various tissues in the body via the systemic circulation.
Indications and Usage
Alpha Lipoic acid shows evidence of being effective in the treatment of diabetic neuropathy and may be useful in treating some other aspects of diabetes. It may help prevent the oxidation of LDL cholesterol and may be protective, generally, against oxidative stress and, specifically, against atherosclerosis, ischemia-reperfusion injury and various radiologic and chemical toxins. It may also be useful in some inborn metabolic disorders. It has been suggested that lipoic acid may slow aging of the brain and that it may be an anti-aging substance, in general.
Research Summary on Alpha Lipoic acid
Supplemental alpha-lipoic acid may lower blood glucose levels. Those with diabetes on antidiabetic medication should have their blood glucose monitored and antidiabetic drug dose appropriately adjusted, if necessary, to avoid possible hypoglycemia.
In some experiments, alpha lipoic acid, administered for up to three months, significantly reversed the increase in nerve vascular resistance. Nerve conduction velocity was entirely restored in some nerve groups after three months of treatment.
In a larger, multi-center, double blind, randomized, placebo-controlled study of 328 patients with type 2 diabetes, significant improvements were recorded in several clinical measures of diabetic polyneuropathy, including pain, numbness, paresthesia and burning sensations. These results were evident after three weeks of intravenous lipoic acid given five times weekly in doses of 600 and 1200 milligrams.
There is evidence, too, that lipoic acid may help prevent or slow the development of the atherosclerosis for which diabetics are at higher risk. It may do this, in part, through a gene-regulatory mechanism that helps prevent endothelial cell activity that has been implicated in the progression of atherosclerosis.
With respect to atherosclerosis, in general, lipoic acid's antioxidant and metabolic effects appear to offer some protection, as demonstrated in various animal models. Recently, researchers demonstrated, in a 16-week randomized trial, that lipoic acid, in oral doses of 600 milligrams daily for eight weeks, significantly inhibits the oxidation of LDL-cholesterol in healthy human subjects. The supplements also significantly reduced levels of F-2 isoprostanes, markers of oxidative stress. In this study, lipoic acid proved to be superior to vitamin E in decreasing levels of plasma protein carbonyls. Protein oxidation and LDL-cholesterol oxidation are implicated in heart disease.
Claims that alpha lipoic acid slows aging of the brain and is an anti-aging substance generally seem to be related to its potent antioxidant properties. Direct proof of anti-aging is lacking, but there is some animal work suggestive of some possible anti-aging effects.
Contraindications
None known.
Precautions
Because of lack of long-term safety data, alpha-lipoic acid should be avoided by pregnant women and nursing mothers.
Those with diabetes and problems with glucose intolerance are cautioned that supplemental alpha-lipoic acid may lower blood glucose levels. Blood glucose should be monitored and antidiabetic drug dose adjusted, if necessary, to avoide possible hypoglycemia.
Adverse Reactions
To date, alpha-lipoic acid in doses up to 600 milligrams daily has been well tolerated.
Interactions
Supplemental alpha-lipoic acid may lower blood glucose levels. Those with diabetes on antidiabetic medication should have their blood glucose monitored and antidiabetic drug dose appropriately adjusted, if necessary, to avoid possible hypoglycemia.
Dosage and administration
Alpha-lipoic acid is available as a racemic mixture of D- and L- entantiomers. Some studies showing significant antioxidant effects have used doses of the racemic mixture of 600 milligrams daily.
Vitamin B6 (Pyridoxine)
Vitamin B6, also called pyridoxine, is one of eight water-soluble B vitamins. The B vitamins help the body to convert carbohydrates into glucose (sugar), which is "burned" to produce energy. These vitamins, often referred to as the B complex, are also essential in the metabolism of fats and protein. B complex vitamins also play an important role in maintaining muscle tone in the gastrointestinal tract and promoting the health of the nervous system, skin, hair, eyes, mouth, and liver
Uses
Heart Disease
Low dietary intake of vitamin B6 is associated with higher risk of having heart disease. This may be related to the fact that vitamin B6, together with vitamin B9 (folic acid) and vitamin B12, help to keep homocysteine levels under control. Homocysteine is an amino acid. Elevated levels of this amino acid are associated with increased risk of heart disease and increased risk of stroke. Preliminary evidence suggests that vitamin B6 may help control blood sugar in people with diabetes. In a study of people with diabetes, those who received pyridoxine alpha-ketoglutarate (a form of vitamin B6) for one month experienced significant reductions in fasting blood sugar levels compared to those who did not receive the supplement. More research in this area is needed before conclusions can be drawn about the relationship between vitamin B6 and diabetes.
Folic acid:
Folic acid deficiency is widespread and is associated with an increased risk for heart disease, cancer, depression and many other disorders. There is no question that folic acid is extremely important to health and well-being. Not only is it important for heart health, mental health and women's health, but also it is now also clear that it affects many other facets of health and disease. Researchers at the Cleveland Clinic Foundation have found that patients with end- stage renal disease have extremely high homocysteine levels and can be protected from cardiovascular events by supplementing with folic acid, vitamins B6 and B12. Diabetes patients tend to have high homocysteine levels and folate is especially important for them. Recent research has also shown that low folate levels (high homocysteine levels) are implicated in age-related hearing loss, psoriasis, and restless leg syndrome.
It is indeed astounding that one single vitamin, folic acid, can have such a profound effect on our health and yet perhaps it is not so surprising when one considers its vital role in DNA synthesis and homocysteine metabolism.
ChromoZinc, therefore, is the indispensable addition in a doctor’s armamentarium while managing diabetes mellitus and diabetic neuropathy.
Posted:
28th December 2006
Reliance Formulation (Pvt.) Ltd., Ahmedabad
For more details on ChromoZinc, please e-mail to
Mr. Mukesh Vankani – General Manager (Marketing & Sales)
28th December 2006
Reliance Formulation (Pvt.) Ltd., Ahmedabad
For more details on ChromoZinc, please e-mail to
Mr. Mukesh Vankani – General Manager (Marketing & Sales)
posted by Reliance Formulation Pvt. Ltd. | 9:11 PM
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